The maluma/takete effect is late: No longitudinal evidence for shape sound symbolism in the first year.

The maluma/takete effect refers to an association between certain language sounds (e.g., /m/ and /o/) and round shapes, and other language sounds (e.g., /t/ and /i/) and spiky shapes. This is an example of sound symbolism and stands in opposition to arbitrariness of language. It is still unknown when sensitivity to sound symbolism emerges. In the present series of studies, we first confirmed that the classic maluma/takete effect would be observed in adults using our novel 3-D object stimuli (Experiments 1a and 1b). We then conducted the first longitudinal test of the maluma/takete effect, testing infants at 4-, 8- and 12-months of age (Experiment 2). Sensitivity to sound symbolism was measured with a looking time preference task, in which infants were shown images of a round and a spiky 3-D object while hearing either a round- or spiky-sounding nonword. We did not detect a significant difference in looking time based on nonword type. We also collected a series of individual difference measures including measures of vocabulary, movement ability and babbling. Analyses of these measures revealed that 12-month olds who babbled more showed a greater sensitivity to sound symbolism. Finally, in Experiment 3, we had parents take home round or spiky 3-D printed objects, to present to 7- to 8-month-old infants paired with either congruent or incongruent nonwords. This language experience had no effect on subsequent measures of sound symbolism sensitivity. Taken together these studies demonstrate that sound symbolism is elusive in the first year, and shed light on the mechanisms that may contribute to its eventual emergence.

Trajectories of Vocabulary Development in Children with Autism Spectrum Disorder Across Multiple Measures.

This longitudinal study examined how receptive and expressive vocabulary assessments capture vocabulary development in children with Autism Spectrum Disorder (ASD) and typically developing (TD) children. Using mixed regression modelling, we explored when children with ASD significantly different from TD children. We also examined the variability of individual trajectories of vocabulary development in children with ASD. Children with ASD showed slowed trajectories and significantly differed from TD children by 24 months on all assessments except for picture-based assessments. Children with ASD also showed high heterogeneity in trajectories, with some showing inconsistent patterns of growth, stagnation, and regression across assessments. This suggests that conclusions based on individual assessments of vocabulary can vary and assessment characteristics must be considered when monitoring vocabulary development.

Utterance-Initial Prosodic Differences Between Statements and Questions in Infant-Directed Speech.

Cross-linguistically, statements and questions broadly differ in syntactic organization. To learn the syntactic properties of each sentence type, learners might first rely on non-syntactic information. This paper analyzed prosodic differences between infant-directed wh-questions and statements to determine what kinds of cues might be available. We predicted there would be a significant difference depending on the first words that appear in wh-questions (e.g., two closed-class words; meaning words from a category that rarely changes) compared to the variety of first words found in statements. We measured F0, duration, and intensity of the first two words in statements and wh-questions in naturalistic speech from 13 mother-child dyads in the Brent corpus of the CHILDES database. Results found larger differences between sentence-types when the second word was an open-class not a closed-class word, suggesting a relationship between prosodic and syntactic information in an utterance-initial position that infants may use to make sentence-type distinctions.

Boosting the input: 9-month-olds' sensitivity to low-frequency phonotactic patterns in novel wordforms.

To learn their first words, infants must attend to a variety of cues that signal word boundaries. One such cue infants might use is the language-specific phonotactics to track legal combinations and positions of segments within a word. Studies have demonstrated that, when tested across statistically high and low phonotactics, infants repeatedly reject the low-frequency wordforms. We explore whether the capacity to access low-frequency phonotactic combinations is available at 9 months when pre-exposed to wordforms containing statistically low combinations of segments. Using a modified head-turn procedure, one group of infants was presented with nonwords with low-frequency complex onsets (dr-), and another group was presented with zero-frequency onset nonwords (dl-). Following pre-exposure and familiarization, infants were then tested on their ability to segment nonwords that contained either the low- or the zero-frequency onsets. Only infants in the low-frequency condition were successful at the task, suggesting some experience with these onsets supports segmentation.

Eleven-Month-Olds Link Sound Properties With Animal Categories.

We examined 11-month-olds' tendency to generalize properties to category members, an ability that may contribute to the inductive reasoning abilities observed in later developmental periods. Across three experiments, we tested 11-month-olds' (N = 113) generalization of properties within the cat and dog categories. In each experiment, infants were familiarized to animal-sound pairings (i.e., dog barking; cat meowing) and tested on this association and the generalization of the sound property to new members of the familiarized categories. After familiarization with a single exemplar, 11-month-olds generalized the sound to new category members that were both highly similar and less similar to the familiarized animal (Experiment 1). When familiarized with mismatched animal-sound pairings (Experiment 2; i.e., dog meowing; cat barking), 11-month-olds did not learn or generalize the sound properties, suggesting that infants have pre-existing expectations about the links between the characteristic sound properties and the animal categories. When familiarized with unfamiliar sound-animal pairings (Experiment 3; i.e., dog-unfamiliar sound), 11-month-olds linked the animals with the novel sounds but did not generalize to new category members. Taken together, these findings highlight the conditions under which young infants generalize properties from one exemplar to other category members.

Does an Early Speech Preference Predict Linguistic and Social-Pragmatic Attention in Infants Displaying and Not Displaying Later ASD Symptoms?

Human infants show a robust preference for speech over many other sounds, helping them learn language and interact with others. Lacking a preference for speech may underlie some language and social-pragmatic difficulties in children with ASD. But, it's unclear how an early speech preference supports later language and social-pragmatic abilities. We show that across infants displaying and not displaying later ASD symptoms, a greater speech preference at 9 months is related to increased attention to a person when they speak at 12 months, and better expressive language at 24 months, but is not related to later social-pragmatic attention or outcomes. Understanding how an early speech preference supports language outcomes could inform targeted and individualized interventions for children with ASD.

Developmental Trajectories of Infants With Multiplex Family Risk for Autism: A Baby Siblings Research Consortium Study.

Importance: Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with different genetic etiologies. Prospective examination of familial-risk infants informs understanding of developmental trajectories preceding ASD diagnosis, potentially improving early detection. Objective: To compare outcomes and trajectories associated with varying familial risk for ASD across the first 3 years of life. Design, Setting, and Participants: This longitudinal, prospective cohort study used data from 11 sites in the Baby Siblings Research Consortium database. Data were collected between 2003 and 2015. Infants who were younger siblings of children with ASD were followed up for 3 years. Analyses were conducted in April 2018. Of the initial 1008 infants from the database, 573 were removed owing to missing necessary data, diagnostic discrepancies, or only having 1 older sibling. Exposures: Number of siblings with ASD. Main Outcomes and Measures: Outcomes included ASD symptoms, cognitive abilities, and adaptive skills. Diagnosis (ASD or no ASD) was given at 36-month outcome. The no-ASD group was classified as atypical (developmental delays and/or social-communication concerns) or typical for some analyses. Generalized linear mixed models examined developmental trajectories by ASD outcome and familial-risk group. Results: In the 435 analyzed participants (age range at outcome, 32-43 months; 246 male [57%]), 355 (82%) were from single-incidence families (1 sibling with ASD and ≥1 sibling without ASD) and 80 (18%) were from multiplex families (≥2 siblings with ASD). There were no significant group differences in major demographics. Children from multiplex families were more likely than those from single-incidence families to be classified as having ASD (29 of 80 [36%] vs 57 of 355 [16%]; 95% CI, 9%-31%; P < .001) and less likely as typical (26 of 80 [33%] vs 201 of 355 [57%]; 95% CI, -36% to -13%; P < .001), with similar rates of atypical classifications (25 of 80 [31%] vs 97 of 355 [27%]; 95% CI, -7% to 15%; P = .49). There were no differences in ASD symptoms between multiplex and single-incidence groups after controlling for ASD outcome (95% CI, -0.02 to 0.20; P = .18). During infancy, differences in cognitive and adaptive abilities were observed based on ASD outcome in the single-incidence group only. At 36 months, the multiplex/no-ASD group had lower cognitive abilities than the single-incidence/no-ASD group (95% CI, -11.89 to -2.20; P = .02), and the multiplex group had lower adaptive abilities than individuals in the single-incidence group after controlling for ASD outcome (95% CI, -9.01 to -1.48; P = .02). Conclusions and Relevance: Infants with a multiplex family history of ASD should be monitored early and often and referred for early intervention at the first sign of concern. Direct examination of genetic contributions to neurodevelopmental phenotypes in infants with familial risk for ASD is needed.

Early motor abilities in infants at heightened versus low risk for ASD: A Baby Siblings Research Consortium (BSRC) study.

Research has identified early appearing differences in gross and fine motor abilities in infants at heightened risk (HR) for autism spectrum disorder (ASD) because they are the younger siblings of children with ASD, and it suggests that such differences may be especially apparent among those HR infants themselves eventually diagnosed with ASD. The present study examined overall and item-level performance on the gross (GM) and fine motor (FM) subscales of the Mullen Scales of Early Learning (MSEL) administered at 6 months to a large, geographically diverse sample of HR infants with varying developmental outcomes (ASD, elevated ADOS without ASD, low ADOS without ASD) and to infants with low ASD risk (low risk [LR]). We also explored whether motor abilities assessed at 6 months predicted ASD symptom severity at 36 months. FM (but not GM) performance distinguished all 3 HR groups from LR infants with the weakest performance observed in the HR-Elevated ADOS children, who exhibited multiple differences from both LR and other HR infants in both gross and fine motor skills. Finally, 6-month FM (but not GM) scores significant predicted 36-month ADOS severity scores in the HR group; but no evidence was found of specific early appearing motor signs associated with a later ASD diagnosis. Vulnerabilities in infants' fine and gross motor skills may have significant consequences for later development not only in the motor domain but in other domains. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Word Level Stress and Lexical Processing in 17-Month-Old Infants.

Detailed representations enable infants to distinguish words from one another and more easily recognize new words. We examined whether 17-month-old infants encode word stress in their familiar word representations. In Experiment 1, infants were presented with pairs of familiar objects while hearing a target label either properly pronounced with the correct stress (e.g., baby /'beɪbi/) or mis-pronounced with the incorrect stress pattern (e.g., baby /beɪ'bi/). Infants mapped both the correctly stressed and mis-stressed labels to the target objects; however, they were slower to fixate the target when hearing the mis-stressed label. In Experiment 2, we examined whether infants appreciate that stress has a nonproductive role in English (i.e., altering the stress of a word does not typically signal a change in word meaning) by presenting infants with a familiar object paired with a novel object while hearing either correctly stressed or mis-stressed familiar words (Experiment 2). Here, infants mapped the correctly stressed label to the familiar object but did not map the mis-stressed label reliably to either the target or distractor objects. These findings suggest that word stress impacts the processing of familiar words, and infants have burgeoning knowledge that altering the stress pattern of a familiar word does not reliably signal a new referent.

Preference for speech in infancy differentially predicts language skills and autism-like behaviors.

Early emerging biases for conspecific vocalizations are a hallmark of early development. Typically developing neonates listen to speech more than many other sounds, including non-biological non-speech sounds, but listen equally to speech and monkey calls. By 3 months of age, however, infants prefer speech over both non-biological non-speech sounds and monkey calls. We examined whether different listening preferences continue to develop along different developmental trajectories and whether listening preferences are related to developmental outcomes. Given the static preference for speech over non-biological non-speech sounds and the dynamic preference for speech over monkey calls between birth and 3 months, we examined whether 9-month-olds prefer speech over non-biological non-speech sounds (Experiment 1) and prefer speech over monkey calls (Experiment 2). We compared preferences for sounds in infants at low risk (SIBS-TD) and infants at high risk (SIBS-A) of autism spectrum disorder (ASD), a heterogeneous population who differ from typically developing infants in their preferences for speech, and examined whether listening preferences predict vocabulary and autism-like behaviors at 12 months for both groups. At 9 months, SIBS-TD listened longer to speech than to non-speech sounds and listened longer to monkey calls than to speech, whereas SIBS-A listened longer to speech than to non-speech sounds but listened equally to speech and monkey calls. SIBS-TD's preferences did not predict immediate developmental outcomes. In contrast, SIBS-A who preferred speech over non-speech or monkey calls had larger vocabularies and fewer markers of autism-like behaviors at 12 months, which could have positive developmental implications.

Not speaking the same language: 17-month-olds shift their perception of novel labels following brief exposure to non-native language.

We examined if and when English-learning 17-month-olds would accommodate Japanese forms as labels for novel objects. In Experiment 1, infants (n = 22) who were habituated to Japanese word-object pairs looked longer at switched test pairs than familiar test pairs, suggesting that they had mapped Japanese word forms to objects. In Experiments 2 (n = 44) and 3 (n = 22), infants were presented with a spoken passage prior to habituation to assess whether experience with a different language would shift their perception of Japanese word forms. Here, infants did not demonstrate learning of Japanese word-object pairs. These findings offer insight into the flexibility of the developing perceptual system. That is, when there is no evidence to the contrary, 17-month-olds will accommodate forms that vary from their typical input but will efficiently constrain their perception when cued to the fact that they are not listening to their native language.

Shifting Preferences for Primate Faces in Neurotypical Infants and Infants Later Diagnosed With ASD.

Infants look at others' faces to gather social information. Newborns look equally at human and monkey faces but prefer human faces by 1 month, helping them learn to communicate and interact with others. Infants later diagnosed with autism spectrum disorder (ASD) look at human faces less than neurotypical infants, which may underlie some deficits in social-communication later in life. Here, we asked whether infants later diagnosed with ASD differ in their preferences for both human and nonhuman primate faces compared to neurotypical infants over their first 2 years of life. We compare infants' relative looking times to human or monkey faces paired with nonface controls (Experiment 1) and infants' total looking times to pairs of human and monkey faces (Experiment 2). Across two experiments, we find that between 6 and 18 months, infants later diagnosed with ASD show a greater downturn (decrease after an initial increase) in looking at both primate faces than neurotypical infants. A decrease in attention to primate faces may partly underlie the social-communicative difficulties in children with ASD and could reveal how early perceptual experiences with faces affect development. Autism Res 2019, 12: 249-262 © 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Looking at faces helps infants learn to interact with others. Infants look equally at human and monkey faces at birth but prefer human faces by 1 month. Infants later diagnosed with ASD who show deficits in social-communication look at human faces less than neurotypical infants. We find that a downturn (decline after an initial increase) in attention to both human and monkey faces between 6 and 18 months may partly underlie the social-communicative difficulties in children with ASD.

Fourteen-month-olds' sensitivity to acoustic salience in minimal pair word learning.

During the first two years of life, infants concurrently refine native-language speech categories and word learning skills. However, in the Switch Task, 14-month-olds do not detect minimal contrasts in a novel object-word pairing (Stager & Werker, 1997). We investigate whether presenting infants with acoustically salient contrasts (liquids) facilitates success in the Switch Task. The first two experiments demonstrate that acoustic differences boost infants' detection of contrasts. However, infants cannot detect the contrast when the segments are digitally shortened. Thus, not all minimal contrasts are equally difficult, and the acoustic properties of a contrast matter in word learning.

Does lexical stress influence 17-month-olds' mapping of verbs and nouns?

English-learning infants attend to lexical stress when learning new words. Attention to lexical stress might be beneficial for word learning by providing an indication of the grammatical class of that word. English disyllabic nouns commonly have trochaic (strong-weak) stress, whereas English disyllabic verbs commonly have iambic (weak-strong) stress. We explored whether 17-month-old infants use word stress to resolve an ambiguous labeling event where objects and actions are equally plausible referents. Infants were habituated to 2 words paired with 2 objects, with each object performing a distinct path action. They were subsequently tested on (a) a change in object but not path action or (b) a change in path action but not the object. When infants were taught verb-friendly iambic labels, their looking times increased both when the action switched and when the object switched. Infants who were taught noun-friendly trochaic labels demonstrated an increase in looking time only when the object switched. These results demonstrate that in ambiguous labeling events infants map iambic labels to both actions and objects, and trochaic labels to the objects but not to the actions, suggesting a bias for words with trochaic stress to refer to objects. Seventeen-month-old infants can use trochaic lexical stress to guide their word learning in ambiguous situations, but iambic stress cues may not preferentially guide infants' mappings of actions or objects. (PsycINFO Database Record

Non-ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study.

We characterized developmental outcomes of a large sample of siblings at familial high-risk of autism spectrum disorder (ASD), who themselves did not have ASD (n = 859), and low-risk controls with no family history of ASD (n = 473). We report outcomes at age 3 years using the Mullen Scales of Early Learning, the Autism Diagnostic Observation Schedule (ADOS), the Autism Diagnostic Interview-Revised (ADI-R) and adaptive functioning on the Vineland Adaptive Behavior Scales. Around 11% of high-risk siblings had mild-to-moderate levels of developmental delay, a rate higher than the low-risk controls. The groups did not differ in the proportion of toddlers with mild-to-moderate language delay. Thirty percent of high-risk siblings had elevated scores on the ADOS, double the rate seen in the low-risk controls. High-risk siblings also had higher parent reported levels of ASD symptoms on the ADI-R and lower adaptive functioning on the Vineland. Males were more likely to show higher levels of ASD symptoms and lower levels of developmental ability and adaptive behavior than females across most measures but not mild-to-moderate language delay. Lower maternal education was associated with lower developmental and adaptive behavior outcomes. These findings are evidence for early emerging characteristics related to the "broader autism phenotype" (BAP) previously described in older family members of individuals with ASD. There is a need for ongoing clinical monitoring of high-risk siblings who do not have an ASD by age 3 years, as well as continued follow-up into school age to determine their developmental and behavioral outcomes. Autism Res 2017, 10: 169-178. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.

Commentary: sex difference differences? A reply to Constantino.

Messinger et al. found a 3.18 odds ratio of male to female ASD recurrence in 1241 prospectively followed high-risk (HR) siblings. Among high-risk siblings (with and without ASD), as well as among 583 low-risk controls, girls exhibited higher performance on the Mullen Scales of Early Learning, as well as lower restricted and repetitive behavior severity scores on the Autism Diagnostic Observation Schedule (ADOS) than boys. That is, female-favoring sex differences in developmental performance and autism traits were evident among low-risk and non-ASD high-risk children, as well as those with ASD. Constantino (Mol Autism) suggests that sex differences in categorical ASD outcomes in Messinger et al. should be understood as a female protective effect. We are receptive to Constantino's (Mol Autism) suggestion, and propose that quantitative sex differences in autism-related features are keys to understanding this female protective effect.

Nine-month-olds use frequency of onset clusters to segment novel words.

Before their first birthday, infants have started to identify and use information about their native language, such as frequent words, transitional probabilities, and co-occurrence of segments (phonotactics), to identify viable word boundaries. These cues can then be used to segment new words from running speech. We explored whether infants are capable of detecting a novel word form using the frequency of occurrence of the onset alone to further characterize the role of phonotactics in speech segmentation. Experiment 1 shows that English-learning 9-month-olds can successfully segment a word from natural speech if the onset is legal in English (i.e., pleet) but not if the onset is illegal (i.e., tleet). Experiment 2 shows that English-learning 9-month-olds are successful at word segmentation when presented with two onset clusters that vary in statistical frequency. Infants familiarized to a high-frequency onset (i.e., trom) were successful at segmenting the target word embedded in speech, but those familiarized to the low-frequency onset (i.e., drom) were unsuccessful. Together, these results show that infants use statistical information from the speech input and that low levels of exposure to onset phonotactics alone might not be sufficient in identifying word boundaries.

Infants' acceptance of phonotactically illegal word forms as object labels.

We investigated 16- and 20-month-olds' flexibility in mapping phonotactically illegal words to objects. Using an associative word-learning task, infants were presented with a training phase that either highlighted or did not highlight the referential status of a novel label. Infants were then habituated to two novel objects, each paired with a phonotactically illegal Czech word. When referential cues were provided, 16-, but not 20-month-olds, formed word-object mappings. In the absence of referential cues, infants of both ages failed to map the novel words. These findings illustrate the complex interplay between infants' developing sound system and their word learning abilities.

Language Differences at 12 Months in Infants Who Develop Autism Spectrum Disorder.

Little is known about early language development in infants who later develop autism spectrum disorder (ASD). We analyzed prospective data from 346 infants, some of whom were at high risk for developing ASD, to determine if language differences could be detected at 12 months of age in the infants who later were diagnosed with ASD. Analyses revealed lower receptive and expressive language scores in infants who later were diagnosed with ASD. Controlling for overall ability to understand and produce single words, a Rasch analysis indicated that infants who later developed ASD had a higher degree of statistically unexpected word understanding and production. At 12 months of age, quantitative and qualitative language patterns distinguished infants who later developed ASD from those who did not.